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Called Paleo in 2009, four years earlyCalled tiny houses in 2010Called microbiome medicine in 2011First recorded FMT for celiac disease, 2012Called Keto in 2013Said Pepsi would put fiber on the can in 2020. It shipped in 2026Called the nickel problem in 2020. The EU began regulating in 2025Called phage therapy for antimicrobial resistanceCalled Paleo in 2009, four years earlyCalled tiny houses in 2010Called microbiome medicine in 2011First recorded FMT for celiac disease, 2012Called Keto in 2013Said Pepsi would put fiber on the can in 2020. It shipped in 2026Called the nickel problem in 2020. The EU began regulating in 2025Called phage therapy for antimicrobial resistance

Standards Developer · Microbiome Researcher · Founder · Cyprus

Always
ahead of
the market.

Karen Pendergrass works where heavy metals meet the microbiome—and where research becomes standards. She founded Heavy Metal Certified, developed microbial metallomics, built Microbiome Medicine, and imagined Swovee before robotics, AI, laser scanning, and large-format 3D printing began converging in the field.

Karen Pendergrass
SUBJECT IDENTIFIEDKAREN PENDERGRASS

The Oracle · On the record

Well, if it isn’t the Oracle herself.

In 2020, Karen told Fred Hart that Pepsi would eventually put fiber and prebiotics on the front of its cans. It shipped in 2026. Fred's greeting stuck.

Fred Hart · Partner & Creative Director, Interact

Open the receipts →

The work

Heavy metals. Microbes. Machines.

Three disciplines, one habit: recognize the system early, follow the evidence all the way through, then build the thing the field will eventually need.

01

Heavy metals

Karen founded Heavy Metal Certified and built Heavy Metal Index to connect toxicology, food categories, regulations, testing, and source evidence. The goal is not fear. It is standards that can survive scrutiny.

Heavy Metal Certified
02

Microbes

Her work in microbiome medicine and microbial metallomics examines how metals alter microbial ecosystems, virulence, host response, and the interventions that might change the course of disease.

Microbial metallomics
03

Machines

Swovee is Karen’s 2017 robotics project: AI, laser scanning, autonomous movement, and large-format 3D printing combined into a terrain-aware construction system called the Rovalizer.

Swovee.com
Heavy Metal Certified mark

A standard—and the work behind the sanctuary

Heavy Metal Certified.

The certification program translates a complicated evidence base into category-specific operating standards. It has also been the work helping Karen feed and care for the Gardens of St. Gertrude cats year after year.

Origin + receipts

The work did not begin with a brand deck.

It began with lived problems, documented calls, and building the infrastructure before the market agreed it was necessary.

2009

Paleo

Called the Paleo diet as a coming trend four years before it broke into the mainstream, then built the certification body that now defines the category.

Follow the record ↗
2012

First recorded FMT for celiac disease

Became the first person on record to receive a fecal microbiota transplant for celiac disease, four years before an "accidental" case was reported as curative.

Read the origin →
2020

Fiber on the front of the can

Told Fred Hart that Pepsi would one day put fiber and prebiotics on the front of its cans and advertise it proudly. He thought I was crazy. It shipped in 2026.

Gardens of St. Gertrude · 501(c)(3)

And 90+ cats.

Karen runs a real cat sanctuary in Cyprus. Tinies grew from the daily reality of feeding, housing, treating, and advocating for those animals. A dollar is not symbolic here. It helps buy the next bag of food.

Ziggy at Gardens of St. GertrudeToshiba at Gardens of St. GertrudeSplotch at Gardens of St. GertrudeA sanctuary cat at Gardens of St. Gertrude

The record

Serious work leaves receipts.

Browse Karen’s publications, documented forecasts, research frameworks, and professional record directly.